Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex
A large protein complex consisting of Atg5, Atg12 and Atg16L1 has recently been shown to be essential for the elongation of isolation membranes (also called phagophores) during mammalian autophagy. However, the precise function and regulation of the Atg12–5-16L1 complex has largely remained unknown....
Gorde:
Egile Nagusiak: | Koutaro Ishibashi, Naonobu Fujita, Eiko Kanno, Hiroko Omori, Tamotsu Yoshimori, Takashi Itoh, Mitsunori Fukuda |
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Formatua: | Artigo |
Hizkuntza: | ingelesa |
Argitaratua: |
2011
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Sarrera elektronikoa: | https://doi.org/10.4161/auto.7.12.18025 https://www.tandfonline.com/doi/pdf/10.4161/auto.7.12.18025?needAccess=true |
Etiketak: |
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Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex
nork: Ishibashi, Koutaro, et al.
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The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy
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Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation
nork: Itoh, Takashi, et al.
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Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation
nork: Takashi Itoh, et al.
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