Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
Epsins are endocytic adaptors with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific membrane proteins. We have now tested the role of the ubiquitously expressed epsin genes, Epn1 and Epn2, by a genetic approach in mice. While either...
Sparad:
| Huvudupphovsmän: | , , , , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | engelska |
| Publicerad: |
2009
|
| Länkar: | https://doi.org/10.1073/pnas.0907008106 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|