Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

Epsins are endocytic adaptors with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific membrane proteins. We have now tested the role of the ubiquitously expressed epsin genes, Epn1 and Epn2, by a genetic approach in mice. While either...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hong Chen, Genevieve Ko, Alessandra Zatti, Giuseppina Di Giacomo, Lijuan Liu, Elisabetta Raiteri, Ezio Perucco, Chiara Collesi, Min Wang, Caroline J. Zeiss, Pietro De Camilli, Ottavio Cremona
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2009
Urunga tuihono:https://doi.org/10.1073/pnas.0907008106
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Ipurangi

https://doi.org/10.1073/pnas.0907008106

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