Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
Epsins are endocytic adaptors with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific membrane proteins. We have now tested the role of the ubiquitously expressed epsin genes, Epn1 and Epn2, by a genetic approach in mice. While either...
Tallennettuna:
Päätekijät: | , , , , , , , , , , , |
---|---|
Aineistotyyppi: | Artigo |
Kieli: | englanti |
Julkaistu: |
2009
|
Linkit: | https://doi.org/10.1073/pnas.0907008106 |
Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|