Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
Epsins are endocytic adaptors with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific membrane proteins. We have now tested the role of the ubiquitously expressed epsin genes, Epn1 and Epn2, by a genetic approach in mice. While either...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2009
|
| Online Access: | https://doi.org/10.1073/pnas.0907008106 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|