Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4

UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection against environmental toxins. The aim of this study was to identify polymorphisms at the human UGT1A gene locus and to characterize their function and potential association w...

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Autori principali: Ursula Ehmer, Arndt Vogel, Jan Karl Schütte, B Krone, Michael P. Manns, Christian P. Strassburg
Natura: Artigo
Lingua:inglese
Pubblicazione: 2004
Accesso online:https://doi.org/10.1002/hep.20131
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.20131
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