Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
We sought to examine mechanisms responsible for increased vasoconstriction that occurs during development of nitroglycerin tolerance. Rabbits were treated for 3 days with nitroglycerin patches (0.4 mg/hr), and their aortic segments were studied in organ chambers. This treatment resulted in attenuate...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1995
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| 在线阅读: | https://doi.org/10.1073/pnas.92.11.5244 |
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