Effects of Macromolecular Crowding on Protein Conformational Changes

Many protein functions can be directly linked to conformational changes. Inside cells, the equilibria and transition rates between different conformations may be affected by macromolecular crowding. We have recently developed a new approach for modeling crowding effects, which enables an atomistic r...

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Hlavní autoři: Hao Dong, Sanbo Qin, Huan‐Xiang Zhou
Médium: Artigo
Jazyk:angličtina
Vydáno: 2010
On-line přístup:https://doi.org/10.1371/journal.pcbi.1000833
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000833&type=printable
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