Effects of Macromolecular Crowding on Protein Conformational Changes

Many protein functions can be directly linked to conformational changes. Inside cells, the equilibria and transition rates between different conformations may be affected by macromolecular crowding. We have recently developed a new approach for modeling crowding effects, which enables an atomistic r...

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Main Authors: Hao Dong, Sanbo Qin, Huan‐Xiang Zhou
格式: Artigo
语言:英语
出版: 2010
在线阅读:https://doi.org/10.1371/journal.pcbi.1000833
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000833&type=printable
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