Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells
Significance Myosin binding protein-C (MyBP-C) is a regulatory protein of heart muscle. Mutations in MyBP-C are frequently associated with heart disease, but the mechanism of action of MyBP-C is poorly understood. By characterizing the effects of its N-terminal domains on the structures of the thin...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2014
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| On-line přístup: | https://doi.org/10.1073/pnas.1413922112 https://www.pnas.org/content/pnas/111/52/18763.full.pdf |
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