Polyamines Regulate c-Myc Translation through Chk2-dependent HuR Phosphorylation
All mammalian cells depend on polyamines for normal growth and proliferation, but the exact roles of polyamines at the molecular level remain largely unknown. The RNA-binding protein HuR modulates the stability and translation of many target mRNAs. Here, we show that in rat intestinal epithelial cel...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2009
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| Online Access: | https://doi.org/10.1091/mbc.e09-07-0550 |
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