Polyamines Regulate c-Myc Translation through Chk2-dependent HuR Phosphorylation

All mammalian cells depend on polyamines for normal growth and proliferation, but the exact roles of polyamines at the molecular level remain largely unknown. The RNA-binding protein HuR modulates the stability and translation of many target mRNAs. Here, we show that in rat intestinal epithelial cel...

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Main Authors: Lan Liu, Jaladanki N. Rao, Tongtong Zou, Lan Xiao, Peng‐Yuan Wang, Douglas J. Turner, Myriam Gorospe, Jian‐Ying Wang
格式: Artigo
语言:英语
出版: 2009
在线阅读:https://doi.org/10.1091/mbc.e09-07-0550
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