Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1–haploinsufficient osteoclast functions
Individuals with neurofibromatosis type 1 (NF1) have a high incidence of osteoporosis and osteopenia. However, understanding of the cellular and molecular basis of these sequelae is incomplete. Osteoclasts are specialized myeloid cells that are the principal bone-resorbing cells of the skeleton. We...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2006
|
| 在線閱讀: | https://doi.org/10.1172/jci29092 http://www.jci.org/articles/view/29092/files/pdf |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|