Application of a Newly Developed High-Sensitivity HBsAg Chemiluminescent Enzyme Immunoassay for Hepatitis B Patients with HBsAg Seroclearance

We modified and automated a highly sensitive chemiluminescent enzyme immunoassay (CLEIA) for surface antigen (HBsAg) detection using a combination of monoclonal antibodies, each for a specific epitope of HBsAg, and by improving an earlier conjugation technique. Of 471 hepatitis B virus (HBV) carrier...

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Bibliographic Details
Main Authors: Noboru Shinkai, Kentaro Matsuura, Fuminaka Sugauchi, Tsunamasa Watanabe, Shuko Murakami, Etsuko Iio, Shintaro Ogawa, Shunsuke Nojiri, Takashi Joh, Yasuhito Tanaka
Format: Artigo
Language:English
Published: 2013
Online Access:https://doi.org/10.1128/jcm.00726-13
https://jcm.asm.org/content/jcm/51/11/3484.full.pdf
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