Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1

The tumor suppressor protein p53 is a pivotal regulator of apoptosis, and prostate cancer cells that lack p53 protein are moderately resistant to apoptotic death by ionizing radiation. Genes encoding the transcription factor <i>early growth response-1</i> (EGR-1) and cytokine tumor necro...

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Main Authors: Mansoor Ahmed, Stephen F. Sells, Kolaparthi Venkatasubbarao, Sana M. Fruitwala, Sumathi Muthukkumar, Cindy Harp, Mohammed Mohiuddin, Vivek M. Rangnekar
格式: Artigo
语言:英语
出版: 1997
在线阅读:https://doi.org/10.1074/jbc.272.52.33056
http://www.jbc.org/article/S0021925818396546/pdf
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