Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1
The tumor suppressor protein p53 is a pivotal regulator of apoptosis, and prostate cancer cells that lack p53 protein are moderately resistant to apoptotic death by ionizing radiation. Genes encoding the transcription factor <i>early growth response-1</i> (EGR-1) and cytokine tumor necro...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1997
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| Online Access: | https://doi.org/10.1074/jbc.272.52.33056 http://www.jbc.org/article/S0021925818396546/pdf |
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