Direct Optical Detection of Viral Nucleoprotein Binding to an Anti-Influenza Aptamer

We have demonstrated label-free optical detection of viral nucleoprotein binding to a polyvalent anti-influenza aptamer by monitoring the surface-enhanced Raman (SERS) spectra of the aptamer-nucleoprotein complex. The SERS spectra demonstrated that selective binding of the aptamer-nucleoprotein comp...

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Main Authors: Pierre Negri, Guojun Chen, Andreas Kage, Andreas Nitsche, Dieter Naumann, Bingqian Xu, Richard A. Dluhy
格式: Artigo
语言:英语
出版: 2012
在线阅读:https://doi.org/10.1021/ac202427e
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