Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs
MHC class II-restricted antigen presentation plays a central role in the immune response against exogenous antigens. The association of invariant (Ii) chain with MHC class II dimers is required for proper antigen presentation to CD4 + T cells by antigen-presenting cells. MHC class II complexes first...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2003
|
| Online Access: | https://doi.org/10.1073/pnas.1131604100 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|