Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs
MHC class II-restricted antigen presentation plays a central role in the immune response against exogenous antigens. The association of invariant (Ii) chain with MHC class II dimers is required for proper antigen presentation to CD4 + T cells by antigen-presenting cells. MHC class II complexes first...
Sábháilte in:
Príomhchruthaitheoirí: | , , , , , , , |
---|---|
Formáid: | Artigo |
Teanga: | Béarla |
Foilsithe / Cruthaithe: |
2003
|
Rochtain ar líne: | https://doi.org/10.1073/pnas.1131604100 |
Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
Bí ar an gcéad duine le trácht a dhéanamh!