PAK signaling in cancer

Transformation of a normal cell to a cancer cell is caused by mutations in genes that regulate proliferation, apoptosis, and invasion. Small GTPases such as Ras, Rho, Rac and Cdc42 orchestrate many of the signals that are required for malignant transformation. The p21-activated kinases (PAKs) are ef...

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Main Authors: Diana Zi Ye, Jeffrey Field
Formato: Artigo
Idioma:inglés
Publicado: 2012
Acceso en liña:https://doi.org/10.4161/cl.21882
https://www.tandfonline.com/doi/pdf/10.4161/cl.21882?needAccess=true
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