The T-cell-receptor repertoire in the synovial fluid of a patient with rheumatoid arthritis is polyclonal.

We have analyzed the T-cell-receptor repertoire expressed in the synovial fluid of a patient with rheumatoid arthritis by using an inverse polymerase chain reaction. Total RNA was isolated from Ficoll-purified mononuclear cells and converted into circularized double-stranded cDNA. Specific amplifica...

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Main Authors: Yasushi Uematsu, Henning Wege, A. H. Straus, Michael Ott, Wilhelm Bannwarth, Jerry S. Lanchbury, G S Panayi, Michael Steinmetz
Formato: Artigo
Idioma:inglés
Publicado: 1991
Acceso en liña:https://doi.org/10.1073/pnas.88.19.8534
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