Lateral Compartmentalization of T Cell Receptor Versus CD45 by Galectin-N-Glycan Binding and Microfilaments Coordinate Basal and Activation Signaling
Lateral compartmentalization of membrane proteins into microdomains regulates signal transduction; however, structural determinants are incompletely understood. Membrane glycoproteins bind galectins in proportion to the number (i.e. NX(S/T) sites) and degree of GlcNAc branching within attached N-gly...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2007
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| 在线阅读: | https://doi.org/10.1074/jbc.m706923200 http://www.jbc.org/article/S0021925820546723/pdf |
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