Genome-Wide Association Study: A Useful Tool to Identify Common Genetic Variants Associated with Drug Toxicity and Efficacy in Cancer Pharmacogenomics

Abstract In recent years, the utilization of genome-wide association study (GWAS) has proved to be a beneficial method to identify novel common genetic variations not only for disease susceptibility but also for drug efficacy and drug-induced toxicity, creating a field of pharmacogenomics studies. I...

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Hlavní autoři: Siew‐Kee Low, Atsushi Takahashi, Taisei Mushiroda, Michiaki Kubo
Médium: Revisão
Jazyk:angličtina
Vydáno: 2014
On-line přístup:https://doi.org/10.1158/1078-0432.ccr-13-2755
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