Metabolic Labeling of Fucosylated Glycans in Developing Zebrafish

Many developmental processes depend on proper fucosylation, but this post-translational modification is difficult to monitor in vivo. Here we applied a chemical reporter strategy to visualize fucosylated glycans in developing zebrafish. Using azide-derivatized analogues of fucose, we metabolically l...

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Main Authors: Karen W. Dehnert, Brendan J. Beahm, Thinh T. Huynh, Jeremy M. Baskin, Scott T. Laughlin, Wei Wang, Peng Wu, Sharon L. Amacher, Carolyn R. Bertozzi
格式: Artigo
語言:英语
出版: 2011
在線閱讀:https://doi.org/10.1021/cb100284d
https://pubs.acs.org/doi/pdf/10.1021/cb100284d
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