Metabolic Labeling of Fucosylated Glycans in Developing Zebrafish
Many developmental processes depend on proper fucosylation, but this post-translational modification is difficult to monitor in vivo. Here we applied a chemical reporter strategy to visualize fucosylated glycans in developing zebrafish. Using azide-derivatized analogues of fucose, we metabolically l...
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Glavni autori: | Karen W. Dehnert, Brendan J. Beahm, Thinh T. Huynh, Jeremy M. Baskin, Scott T. Laughlin, Wei Wang, Peng Wu, Sharon L. Amacher, Carolyn R. Bertozzi |
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Format: | Artigo |
Jezik: | engleski |
Izdano: |
2011
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Online pristup: | https://doi.org/10.1021/cb100284d https://pubs.acs.org/doi/pdf/10.1021/cb100284d |
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