Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2
The protease-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin. We investigated the expression of PAR-2 and the role of trypsin in cell proliferation in human colon cancer cell lines. A total of 10 cell lines were tested for expression of PAR-2 mRN...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2001
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| 在线阅读: | https://doi.org/10.1054/bjoc.2001.1976 https://www.nature.com/articles/6691976.pdf |
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