Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

Deficiency of early components of the classical pathway of complement, particularly C1q, predisposes to the development of systemic lupus erythematosus. Several studies have suggested an association between the classical complement pathway and the clearance of apoptotic cells. Mice with a targeted d...

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Hauptverfasser: Alma J. Nauta, Leendert A. Trouw, Mohamed R. Daha, Odette Tijsma, Rienk Nieuwland, Wilhelm Schwaeble, Alexandre R. Gingras, Alberto Mantovani, Erik Hack, Anja Roos
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2002
Online-Zugang:https://doi.org/10.1002/1521-4141(200206)32:6<1726::aid-immu1726>3.0.co;2-r
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