Direct binding of C1q to apoptotic cells and cell blebs induces complement activation
Deficiency of early components of the classical pathway of complement, particularly C1q, predisposes to the development of systemic lupus erythematosus. Several studies have suggested an association between the classical complement pathway and the clearance of apoptotic cells. Mice with a targeted d...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2002
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| Online Access: | https://doi.org/10.1002/1521-4141(200206)32:6<1726::aid-immu1726>3.0.co;2-r |
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