Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

Deficiency of early components of the classical pathway of complement, particularly C1q, predisposes to the development of systemic lupus erythematosus. Several studies have suggested an association between the classical complement pathway and the clearance of apoptotic cells. Mice with a targeted d...

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Xehetasun bibliografikoak
Egile Nagusiak:	Alma J. Nauta, Leendert A. Trouw, Mohamed R. Daha, Odette Tijsma, Rienk Nieuwland, Wilhelm Schwaeble, Alexandre R. Gingras, Alberto Mantovani, Erik Hack, Anja Roos
Formatua:	Artigo
Hizkuntza:	ingelesa
Argitaratua:	2002
Sarrera elektronikoa:	https://doi.org/10.1002/1521-4141(200206)32:6<1726::aid-immu1726>3.0.co;2-r
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
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Argitaratua: (2003)

The membrane attack complex of complement induces caspase activation and apoptosis
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Argitaratua: (2002)

Specific Inhibition of the Classical Complement Pathway by C1q-Binding Peptides
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Argitaratua: (2001)

Maturation of dendritic cells abrogates C1q production in vivo and in vitro
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Argitaratua: (2004)

Opsonization with C1q and Mannose-Binding Lectin Targets Apoptotic Cells to Dendritic Cells
nork: Alma J. Nauta, et al.
Argitaratua: (2004)

Mini‐review: A pivotal role for innate immunity in the clearance of apoptotic cells
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The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?
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The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?
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Properdin Binds to Late Apoptotic and Necrotic Cells Independently of C3b and Regulates Alternative Pathway Complement Activation
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Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
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Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
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Mannose‐binding lectin engagement with late apoptotic and necrotic cells
nork: Alma J. Nauta, et al.
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C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited.
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Membrane blebbing and apoptotic bodies in cerebellar cells
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Blebs and Apoptotic Bodies Are B Cell Autoantigens
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C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack
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Evidence That Complement Protein C1q Interacts with C-Reactive Protein through Its Globular Head Region
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Correction: C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack.
nork: Trouw, Leendert A., et al.
Argitaratua: (2020)

The Globular Heads of C1q Specifically Recognize Surface Blebs of Apoptotic Vascular Endothelial Cells
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Argitaratua: (2001)

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy
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Apoptotic cell blebs – repositories of autoantigens and contributors to immune context
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Activated complement components and complement activator molecules on the surface of cell‐derived microparticles in patients with rheumatoid arthritis and healthy individuals
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Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals
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C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation
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The C4b-binding Protein-Protein S Complex Inhibits the Phagocytosis of Apoptotic Cells
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Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb
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Argitaratua: (2020)

Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb
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Argitaratua: (2020)

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation
nork: Katrin Färber, et al.
Argitaratua: (2008)

Production of complement components by cells of the immune system
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Argitaratua: (2017)

Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation
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Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation
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Regulation of Complement Activation by C-Reactive Protein: Targeting of the Inhibitory Activity of C4b-Binding Protein
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The lectin pathway of complement activation contributes to protection from West Nile virus infection
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C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production
nork: Fraser, Deborah A., et al.
Argitaratua: (2009)

C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production
nork: Deborah A. Fraser, et al.
Argitaratua: (2009)

The lectin pathway of complement activation contributes to protection from West Nile virus infection
nork: Fuchs, Anja, et al.
Argitaratua: (2011)

Human intrahepatic biliary epithelial cells engulf blebs from their apoptotic peers
nork: Rong, G-H, et al.
Argitaratua: (2013)

Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences
nork: Mahler, Michael, et al.
Argitaratua: (2013)

Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences
nork: Michael Mähler, et al.
Argitaratua: (2013)

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation
nork: Umakhanth Venkatraman Girija, et al.
Argitaratua: (2013)