Fast Statistical Alignment

We describe a new program for the alignment of multiple biological sequences that is both statistically motivated and fast enough for problem sizes that arise in practice. Our Fast Statistical Alignment program is based on pair hidden Markov models which approximate an insertion/deletion process on...

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Bibliografiske detaljer
Main Authors: Robert K. Bradley, Adam Roberts, Michael Smoot, Sudeep Juvekar, Jaeyoung Do, Colin N. Dewey, Ian Holmes, Lior Pachter
Format: Artigo
Sprog:engelsk
Udgivet: 2009
Online adgang:https://doi.org/10.1371/journal.pcbi.1000392
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000392&type=printable
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