Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour

Epigenetic alterations in the 11p15.5 imprinted gene cluster are frequent in human cancers and are associated with disordered imprinting of insulin-like growth factor (IGF)2 and H19. Recently, an imprinted gene cluster at 14q32 has been defined and includes two closely linked but reciprocally imprin...

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Main Authors: Dewi Astuti, Farida Latif, Kate Wagner, Dean Gentle, Wendy N. Cooper, Daniel Catchpoole, Richard G. Grundy, Anne C. Ferguson‐Smith, Eamonn R. Maher
Format: Artigo
Jezik:angleščina
Izdano: 2005
Online dostop:https://doi.org/10.1038/sj.bjc.6602478
https://www.nature.com/articles/6602478.pdf
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