p21-activated Kinase 6 (PAK6) Inhibits Prostate Cancer Growth via Phosphorylation of Androgen Receptor and Tumorigenic E3 Ligase Murine Double Minute-2 (Mdm2)
The androgen receptor (AR) signaling pathway plays a crucial role in the development and growth of prostate malignancies. Regulation of AR homeostasis in prostate tumorigenesis has not yet been fully characterized. In this study, we demonstrate that p21-activated kinase 6 (PAK6) inhibits prostate tu...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2012
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| 在線閱讀: | https://doi.org/10.1074/jbc.m112.384289 http://www.jbc.org/article/S0021925820464506/pdf |
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