Pro-survival Function of Akt/Protein Kinase B in Prostate Cancer Cells

Tumor necrosis factor superfamily member TRAIL/Apo-2L has recently been shown to induce apoptosis in transformed and cancer cells. Some prostate cancer cells express constitutively active Akt/protein kinase B due to a complete loss of lipid phosphatase PTEN gene, a negative regulator of phosphatidyl...

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Main Authors: Hitesh Thakkar, Xufeng Chen, Frazier Tyan, Suzanna Gim, Heather Robinson, Calvin Lee, Sanjay Pandey, Chichi Nwokorie, Nneka C. Onwudiwe, Ruchi Srivastava
Formato: Artigo
Idioma:inglés
Publicado: 2001
Acceso en liña:https://doi.org/10.1074/jbc.m103321200
http://www.jbc.org/article/S0021925820740822/pdf
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