Pro-survival Function of Akt/Protein Kinase B in Prostate Cancer Cells
Tumor necrosis factor superfamily member TRAIL/Apo-2L has recently been shown to induce apoptosis in transformed and cancer cells. Some prostate cancer cells express constitutively active Akt/protein kinase B due to a complete loss of lipid phosphatase PTEN gene, a negative regulator of phosphatidyl...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2001
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| Online Access: | https://doi.org/10.1074/jbc.m103321200 http://www.jbc.org/article/S0021925820740822/pdf |
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