Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells
This report describes an unbiased method for systematically determining gene function in mammalian cells. A total of 20,704 predicted human full-length cDNAs were tested for induction of the IL-8 promoter. A number of genes, including those for cytokines, receptors, adapters, kinases, and transcript...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | 英语 |
出版: |
2003
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在線閱讀: | https://doi.org/10.1073/pnas.1932773100 |
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