A Novel Hydrogen Sulfide Prodrug, <scp>SG</scp>1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

A Novel Hydrogen Sulfide Prodrug, <scp>SG</scp>1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

Summary Recent studies demonstrate robust molecular cross talk and signaling between hydrogen sulfide (H 2 S) and nitric oxide ( NO ). Heart failure ( HF ) patients are deficient in both H 2 S and NO , two molecules that are critical for cardiovascular homeostasis. A phase I clinical trial of a nove...

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书目详细资料
Main Authors:	David J. Polhemus, Zhen Li, Christopher B. Pattillo, Gabriel Gojon, Tony Giordano, Henry Krum
格式:	Artigo
语言:	英语
出版:	2015
在线阅读:	https://doi.org/10.1111/1755-5922.12128 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1755-5922.12128
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