Bisphosphonates and breast carcinoma

The skeleton is a common site of breast carcinoma metastasis; 75% of patients with breast carcinoma demonstrate bone metastases at autopsy. The lytic destruction of bone in these patients is due to excessive osteoclastic activity. By reducing osteoclastic activity, bisphosphonates inhibit bone resor...

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主要作者: Allan Lipton
格式: Revisão
语言:英语
出版: 1997
在线阅读:https://doi.org/10.1002/(sici)1097-0142(19971015)80:8+<1668::aid-cncr17>3.3.co;2-5
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/%28SICI%291097-0142%2819971015%2980%3A8%20%3C1668%3A%3AAID-CNCR17%3E3.0.CO%3B2-Y
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