Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42
Amyloid fibrils associated with Alzheimer's disease and a wide range of other neurodegenerative diseases have a cross β-sheet structure, where main chain hydrogen bonding occurs between β-strands in the direction of the fibril axis. The surface of the β-sheet has pronounced ridges and grooves w...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , , , , |
---|---|
Fformat: | Artigo |
Iaith: | Saesneg |
Cyhoeddwyd: |
2006
|
Mynediad Ar-lein: | https://doi.org/10.1021/bi052485f |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|
Byddwch y cyntaf i adael sylw!