Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferase.
Mouse cells deficient in the enzyme hypoxanthine phosphoribosyltransferase (HPRT; EC 2.4.2.8) have been transfected with total human DNA, and cells producing human enzyme were isolated by growth in selective medium. DNA from several such cell lines has been used to generate secondary transfectants t...
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| Main Authors: | , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1982
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| 在线阅读: | https://doi.org/10.1073/pnas.79.16.5038 |
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