Combination of RAF and MEK Inhibition for the Treatment of BRAF-Mutated Melanoma: Feedback Is Not Encouraged

Míreanna comhchosúla

• (V600E)BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
  de réir: Pratilas, Christine A., et al.
  Foilsithe / Cruthaithe: (2009)
• ^V600E BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
  de réir: Christine A. Pratilas, et al.
  Foilsithe / Cruthaithe: (2009)
• Efficacy of Intermittent Combined RAF and MEK Inhibition in a Patient with Concurrent BRAF- and NRAS-Mutant Malignancies
  de réir: Abdel-Wahab, Omar, et al.
  Foilsithe / Cruthaithe: (2014)
• Efficacy of Intermittent Combined RAF and MEK Inhibition in a Patient with Concurrent BRAF- and NRAS-Mutant Malignancies
  de réir: Omar Abdel‐Wahab, et al.
  Foilsithe / Cruthaithe: (2014)
• Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
  de réir: Flaherty, Keith T., et al.
  Foilsithe / Cruthaithe: (2012)