Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells

The anti-tumoral effects of cannabinoids have been described in different tumor systems, including pancreatic adenocarcinoma, but their mechanism of action remains unclear. We used cannabinoids specific for the CB1 (ACPA) and CB2 (GW) receptors and metabolomic analyses to unravel the potential pathw...

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Bibliographische Detailangaben
Hauptverfasser: Ilaria Dando, Massimo Donadelli, C. Costanzo, Elisa Dalla Pozza, Angelo D’Alessandro, Lello Zolla, Marta Palmieri
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2013
Online-Zugang:https://doi.org/10.1038/cddis.2013.151
https://www.nature.com/articles/cddis2013151.pdf
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