IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

Multiple studies have shown that plasma levels of the pro-inflammatory cytokine interleukin-6 (IL-6) are elevated in patients with important and prevalent adverse health conditions, including atherosclerosis, diabetes, obesity, obstructive sleep apnea, hypertension, and frailty. Higher plasma levels...

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Hlavní autoři: Laura L. Dugan, Sameh S. Ali, Grigoriy Shekhtman, Amanda J. Roberts, Jacinta Lucero, Kevin L. Quick, M. Margarita Behrens
Médium: Artigo
Jazyk:angličtina
Vydáno: 2009
On-line přístup:https://doi.org/10.1371/journal.pone.0005518
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005518&type=printable
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