A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer

A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer

<b>Background:</b> Germline mutations in the Chek2 kinase gene (<i>CHEK2</i>) have been associated with a range of cancer types. Recently, a large deletion of exons 9 and 10 of <i>CHEK2</i> was identified in several unrelated patients with breast cancer of Czech o...

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Hlavní autoři: Cezary Cybulski, Dominika Wokołorczyk, Tomasz Huzarski, Tomasz Byrski, Jacek Gronwald, Bohdan Górski, Tadeusz Dębniak, Bartłomiej Masojć, Anna Jakubowska, Bartłomiej Gliniewicz, A. Sikorski, Małgorzata Stawicka, Dariusz Godlewski, Zbigniew Kwias, Andrzej Antczak, K Krajka, Wojciech Lauer, Marek Sosnowski, Paulina Sikorska‐Radek, Krzysztof Bar, Robert Klijer, Romuald Zdrojowy, Bartosz Małkiewicz, Wen‐Chien Ko, Tomasz Borkowski, Marek Szwiec, Steven A. Narod, Jan Lubiński
Médium: Artigo
Jazyk:angličtina
Vydáno: 2006
On-line přístup:https://doi.org/10.1136/jmg.2006.044974
https://jmg.bmj.com/content/jmedgenet/43/11/863.full.pdf
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https://doi.org/10.1136/jmg.2006.044974
https://jmg.bmj.com/content/jmedgenet/43/11/863.full.pdf

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