A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer

Background: Germline mutations in the Chek2 kinase gene (CHEK2) have been associated with a range of cancer types. Recently, a large deletion of exons 9 and 10 of CHEK2 was identified in several unrelated patients with breast cancer of Czech o...

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Hlavní autoři:	Cezary Cybulski, Dominika Wokołorczyk, Tomasz Huzarski, Tomasz Byrski, Jacek Gronwald, Bohdan Górski, Tadeusz Dębniak, Bartłomiej Masojć, Anna Jakubowska, Bartłomiej Gliniewicz, A. Sikorski, Małgorzata Stawicka, Dariusz Godlewski, Zbigniew Kwias, Andrzej Antczak, K Krajka, Wojciech Lauer, Marek Sosnowski, Paulina Sikorska‐Radek, Krzysztof Bar, Robert Klijer, Romuald Zdrojowy, Bartosz Małkiewicz, Wen‐Chien Ko, Tomasz Borkowski, Marek Szwiec, Steven A. Narod, Jan Lubiński
Médium:	Artigo
Jazyk:	angličtina
Vydáno:	2006
On-line přístup:	https://doi.org/10.1136/jmg.2006.044974 https://jmg.bmj.com/content/jmedgenet/43/11/863.full.pdf
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A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer

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