p53, Oxidative Stress, and Aging
Mammalian aging is associated with elevated levels of oxidative damage of DNA, proteins, and lipids as a result of unbalanced prooxidant and antioxidant activities. Accumulating evidence indicates that oxidative stress is a major physiological inducer of aging. p53, the guardian of the genome that i...
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Hlavní autoři: | , |
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Médium: | Revisão |
Jazyk: | angličtina |
Vydáno: |
2010
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On-line přístup: | https://doi.org/10.1089/ars.2010.3644 |
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