Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids

The complex cellular networks within tumors, the cytokine milieu, and tumor immune escape mechanisms affecting infiltration and anti-tumor activity of immune cells are of great interest to understand tumor formation and to decipher novel access points for cancer therapy. However, cellular in vitro a...

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Hlavní autoři: Ariane Giannattasio, Sandra Weil, Stephan Kloeß, Nariman Ansari, Ernst H. K. Stelzer, Adelheid Cerwenka, Alexander Steinle, Ulrike Koehl, Joachim Koch
Médium: Artigo
Jazyk:angličtina
Vydáno: 2015
On-line přístup:https://doi.org/10.1186/s12885-015-1321-y
https://bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-015-1321-y
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