Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11‐q13 duplication autism spectrum disorder

Abstract Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) that bioaccumulate in lipid‐rich tissues are of concern as developmental neurotoxicants. Epigenetic mechanisms such as DNA methylation act at the interface of genetic a...

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Auteurs principaux: Michelle M. Mitchell, Rima Woods, Lai‐Har Chi, Rebecca J. Schmidt, Isaac N. Pessah, Paul J. Kostyniak, Janine M. LaSalle
Format: Artigo
Langue:anglais
Publié: 2012
Accès en ligne:https://doi.org/10.1002/em.21722
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