Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11‐q13 duplication autism spectrum disorder

Abstract Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) that bioaccumulate in lipid‐rich tissues are of concern as developmental neurotoxicants. Epigenetic mechanisms such as DNA methylation act at the interface of genetic a...

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Bibliographic Details
Main Authors: Michelle M. Mitchell, Rima Woods, Lai‐Har Chi, Rebecca J. Schmidt, Isaac N. Pessah, Paul J. Kostyniak, Janine M. LaSalle
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1002/em.21722
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