BLIMP1 regulates cell growth through repression of p53 transcription

Tight regulation of p53 is essential for maintaining normal cell growth. Here we report that BLIMP1 acts in an autoregulatory feedback loop that controls p53 activity through repression of p53 transcription. p53 binds to and positively regulates BLIMP1, which encodes for a known B cell transcription...

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Main Authors: Junli Yan, Jianming Jiang, Ching Aeng Lim, Qiang Wu, Huck‐Hui Ng, Keh-Chuang Chin
格式: Artigo
语言:英语
出版: 2007
在线阅读:https://doi.org/10.1073/pnas.0605562104
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