Alkaline Phosphatase Knock-Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia

Alkaline Phosphatase Knock-Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia

Abstract Hypophosphatasia is an inborn error of metabolism characterized by deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP) and skeletal disease due to impaired mineralization of cartilage and bone matrix. We investigated two independently generated TNSALP gen...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: K N Fedde, Libby A. Blair, Julie Silverstein, Stephen P. Coburn, Lawrence M. Ryan, Robert S. Weinstein, Katrina G. Waymire, Sonoko Narisawa, José Luís Millán, Grant R. MacGregor, Michael P. Whyte
Format: Artigo
Idioma:anglès
Publicat: 1999
Accés en línia:https://doi.org/10.1359/jbmr.1999.14.12.2015
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Internet

https://doi.org/10.1359/jbmr.1999.14.12.2015

Ítems similars